Serum uric acid levels are altered by kidney disorders because the kidneys play a dominant role in uric acid excretion. Here, major kidney disorders which accompany hyperuricemia or hypouricemia, including their pathophysiology, are discussed. Chronic kidney disease (CKD) and hyperuricemia are frequently associated, but recent clinical trials have not supported the pathogenic roles of hyperuricemia … Leggi tutto
Editoriale AJKD Vol XX | Iss XX | Month 2022 In this issue of AJKD, Wang et al1 report on the incidence, trends, and consequences of treatment of posttransplant hyperparathyroidism in a nationwide registry encompassing 30,127 Medicare-insured US patients who received a first kidney transplant. …In clinical practice, we want to identify patients with negative … Leggi tutto
The prevalence of urolithiasis has increased worldwide over the past decades (1,2). The recently updatedguidelines on urolithiasis from the European Association of Urology (EAU) (3) represent a landmarkadvancement in the treatment of a common clinical condition because they address both the associatedrisks of urolithiasis beyond urolithiasis itself and the need for follow-up. Risks of urolithiasis … Leggi tutto
ORIGINAL PAPER – SUPPLEMENTARY MATERIALS to the ‘Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group.’ 0
Renal tubular acidosis (RTA) refers to a group of disorders of multiple etiology characterised by a hyperchloremic, normal anion-gap metabolic acidosis caused by different defects affecting several mechanisms of urinary acidification: an impaired secretion of protons by collecting duct in distal hypokalemic RTA (type 1), impaired resorption of bicarbonate in proximal RTA (type 2), a … Leggi tutto