Renal abnormalities observed in Beckwith–Wiedemann syndrome include medullary dysplasia, nephrocalcinosis, medullary sponge kidney, and nephromegaly. Up to 10% of patients with congenital hemihypertrophy have medullary sponge kidney, a condition frequently associated with urolithiasis. 0
Background and objectives: In medullary sponge kidney (MSK)—a common malformative renal condition in patients with calcium nephrolithiasis—hypercalciuria, incomplete distal renal tubular acidosis, and hypocitraturia are common. Clinical conditions with concomitant hypercalciuria and/or incomplete distal renal tubular acidosis are almost invariably associated with bone disease, making osteopathy highly likely in MSK, too. Patients with MSK have … Leggi tutto