SGLT2i ed acido urico
da: Altered Serum Uric Acid Levels in Kidney Disorders, una diapo sui GLIFLAZONI!! e l’ac urico! 0
Kidney Stone Academy
Un corso on line, oramai non più FAD, sulla Fisiopatologia della Calcolosi Renale. GLi AA sono la sicurezza che il corso vale assolutamente la pena di essere visto. https://medicalfree.it/corso/fisiopatologia-della-calcolosi-renale Marco Lombardi
Altered Serum Uric Acid Levels in Kidney Disorders
Serum uric acid levels are altered by kidney disorders because the kidneys play a dominant role in uric acid excretion. Here, major kidney disorders which accompany hyperuricemia or hypouricemia, including their pathophysiology, are discussed. Chronic kidney disease (CKD) and hyperuricemia are frequently associated, but recent clinical trials have not supported the pathogenic roles of hyperuricemia … Leggi tutto
‘Bad dietary habits’ and recurrent calcium oxalate nephrolithiasis
Case report: A 32-year-old truck driver had previously been treated with allopurinol because of hyperuricaemia and gouty =Protein consumption (g/day) arthritis. After having first formed a kidney stone at (adapted from [5]); age 20, he had passed calculi annually for 8 years before he finally underwent ESWL for bilateral radio- it amounted to 108.1 g … Leggi tutto
2 – Nephrocalcinosis and urolithiasis in children Kidney International (2012) 82, 493–497; doi:10.1038/ki.2012.142
Correction to: Kidney International (2011) 80:1278–1291; doi:10.1038/ki.2011.336 In the above-cited article, Table 2 was published with incorrect alignment of age ranges and erroneous unit changes concerning the cystine and urate excretion levels. The urate gram units needed to be multiplied by 10. In Table 1, the diagnosis related to NPT2a mutations should read ‘Urolithiasis, osteoporosis, … Leggi tutto
Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group
Diet interventions may reduce the risk of urinary stone formation and its recurrence, but there is no conclusive consensus in the literature regarding the effectiveness of dietary interventions and recommendations about specific diets for patients with urinary calculi. The aim of this study was to review the studies reporting the effects of different dietary interventions … Leggi tutto
Net Acid Excretion and Urinary Organic Anions in Idiopathic Uric Acid Nephrolithiasis
Subjects with idiopathic uric acid nephrolithiasis had lower urine pH (5.5 versus 5.9; P,0.001) andhigher net acid excretion (60 versus 43 mEq/24 h; P,0.001), with the excess H+ carried by nonammoniumbuffers. In all subjects, there was a positive relationship of net acid excretion with higher body mass indexin spite of strictly controlled equivalent dietary acid … Leggi tutto
Net Acid Excretion and Urinary Organic Anions in Idiopathic Uric Acid Nephrolithiasis
Higher acid load to the kidney, resulting in higher urinary net acid excretion, is an important factor inthe pathogenesis of idiopathic uric acid nephrolithiasis.Clin J Am Soc Nephrol 14: 411–420, 2019. doi: https://doi.org/10.2215/CJN.10420818 0
Genetics of kidney stone disease
Kidney stone disease (nephrolithiasis) is a common problem that can be associated with alterations in urinary solute composition including hypercalciuria. Studies suggest that the prevalence of monogenic kidney stone disorders, including renal tubular acidosis with deafness, Bartter syndrome, primary hyperoxaluria and cystinuria, in patients attending kidney stone clinics is ∼15%. However, for the majority of … Leggi tutto
Genetics of kidney stone disease—Polygenic meets monogenic
Kidney stone disease comprising nephrolithiasis and nephrocalcinosis is a clinical syndrome of increasing prevalence with remarkable heterogeneity. Stone composition, age of manifestation, rate of recurrence, and impairment of kidney function varies with underlying etiologies. While calcium-based kidney stones account for the vast majority their etiology is still poorly understood. Recent studies underline the notion that … Leggi tutto