Nephrolithiasis remains a formidable health problem in the United States and worldwide. A very important butunderaddressed area in nephrolithiasis is the accompanying bone disease. Epidemiologic studies have shown that osteoporotic fractures occur more frequently in patients with nephrolithiasis than in the general population. Decreased bone mineral density and defects in bone remodeling are commonly encountered … Leggi tutto
Objective and design: The prevalence and the effects of hypercalciuria on bone in patients with primaryosteoporosis are poorly defined. We therefore retrospectively analyzed the data of 241 otherwisehealthy women. They were 45–88 years of age and had been referred for their first visit to ourUnit for Metabolic Bone Diseases over a 2-year period because of … Leggi tutto
Context: Diabetes mellitus is a risk factor for nephrolithiasis. A recent observational study found that in patients with type 2 diabetes (T2D), SGLT2 inhibitor use was associated with a 49% lower risk of nephrolithiasis compared with GLP-1 receptor agonists. Objective: We examined the association between nephrolithiasis and the SGLT2 inhibitor empagliflozin, using existing data from … Leggi tutto
Figura esplicativa del maggior rischio di sviluppare CKD negli stone former nel distretto di Olmsted.
The prevalence and incidence of nephrolithiasis is reported to be increasing across the world. Herein, we review information regarding stone incidence and prevalence from a global perspective. A literature search using PubMed and Ovid was performed to identify peer-reviewed journal articles containing information on the incidence and prevalence of kidney stones. Key words used included … Leggi tutto
Commento al lavoro di M Bargagli su Tolvaptan nei paz con ADPKD e rischio litogeno.
Nephrolithiasis research and care have been focused on biochemical changes in urinary solute excretion leading to stone formation, but abnormalities in urine chemistry alone do not explain many aspects of the condition of patients with kidney stone disease. Evidence exists of an association with metabolic syndrome, obesity, diabetes and hypertension, and of enhanced risk of … Leggi tutto
Il caso presentato sottolinea come un deficit di APRT non riconosciuto, non solo possa portare ad insufficienza renale terminale, ma esponga il paziente ad un rischio elevato di fallimento del trapianto renale; ciò è ancora più inaccettabile se si considera l’efficacia, la semplicità e l’economicità del trattamento. 0
Percorso Diagnostico Terapeutico della Colica (Flank Pain)